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Antibody & Antigen

The Meaning of Negative of Antibody of Second Liver Surface

When you check the liver, you will find that there is a hepatitis B surface antibody on the test results list. Some people are positive for hepatitis B surface antibody, while others are negative. Some people will have doubts: What is hepatitis B surface antibody? What does it mean that the surface antibody of hepatitis B is negative? Is it serious to be negative?

1. What is hepatitis B surface antibody?

Hepatitis B surface antibody is an antibody produced after the surface antigen of hepatitis B virus stimulates the immune system of human body. To some extent, it can prevent hepatitis B virus from infecting human body, so that people will not suffer from hepatitis B when they are attacked by hepatitis B virus. Therefore, anti -HBs is a neutralizing antibody with specific protective function, which indicates that the body has produced immunity.

2. What is hepatitis B surface antibody negative?

Negative surface antibody to hepatitis B is a result that people often have in clinical examination of the liver, which indicates that the human body has no immunity, no protection against hepatitis B virus and can't resist the invasion of hepatitis B virus. This is usually manifested in two situations:

(1) Patients are not infected with hepatitis B, but there are no protective antibodies in their bodies. Generally, this kind of situation requires hepatitis B vaccination. After vaccination, the positive rate of human hepatitis B surface antibody (anti-HBs) is over 95%, and the effective protection period varies from person to person. Some can be as long as 5-10 years, while others are only 2-3 years.

Therefore, doctors suggest that the antibody should be checked every 2-3 years after it is produced in the body. If the antibody disappears in the body or the antibody low degree is less than 10, it is necessary to vaccinate hepatitis B vaccine booster in time. The higher the antibody titer, the stronger the immunity and the longer the duration of immune protection.

(2) The patient is infected with hepatitis B virus, and hepatitis B surface antigen is positive. Hepatitis B surface antigen and hepatitis B surface antibody are mutually exclusive and will not exist at the same time, so hepatitis B surface antibody is negative. In this case, it is necessary to combine HBV-DNA test and liver function test to judge whether the condition is serious, and then take scientific and standardized treatment.

To sum up, when hepatitis B surface antibody is negative in liver examination, attention must be paid to it, and further measurement should be carried out under the guidance of a regular professional doctor, and standardized treatment should be carried out if necessary.

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